SAPHO syndrome with rapidly progressing destructive spondylitis: two cases treated surgically

SAPHO syndrome treated with pamidronate.

A middle aged man presented with a 4 year history of painful swelling of both knees and pustular acne on his back. The MRI scan of the knees showed gross synovitis, so did the histopathology of the synovium. A diagnosis of SAPHO syndrome was made and he was treated with IV pamidronate. His pain reduced and acne completely cleared up on therapy. A dermatologist has rarely made a diagnosis of SAP...

Two hundred and one cases of intracranial tuberculoma treated surgically.

Of 38,510 patients admitted to the Neurosurgical Clinic of Bucharest during the 23-year period 1935-57, 2,757 were operated upon for expanding intracranial lesions. These included 201 cases of tuberculoma in patients of ages varying from 3 months to 68 years, the highest incidence being recorded under 30 years of age, particularly in the age group below 20 (Table I). The relative frequency of t...

SAPHO Syndrome

Correction: Rapidly Progressing Myelodysplastic Syndrome Initially Presenting as Acute Leukemia

[This corrects the article DOI: 10.7759/cureus.1096.].

Rapidly Progressing Myelodysplastic Syndrome Initially Presenting as Acute Leukemia

Myelodysplastic syndrome (MDS) refers to a group of various stem cell disorders, characterized by dysplastic and ineffective production in one or more cell lines. In general, MDS tends to present slowly over months to years and is commonly detected with routine bloodwork by primary care physicians. Patients may be asymptomatic and depending on age, comorbidities and risk classification of MDS m...